Aims and scope

Aims

Cancer & Metabolism aims to serve as a venue for publication of rigorous manuscripts investigating the links between metabolism and cancer. Our goal is to publish manuscripts that serve the cancer metabolism community: for example, by delineating new mechanisms into the control of metabolism in cancer cells or tumor stromal cells, identifying new relationships between circulating metabolites and cancer progression, or elucidating metabolic cross talk between different cell types within tumors. Rigor and reproducibility are central priorities for publication, and journal policies require experiments that are reproducible across multiple cell lines and, if applicable, with >1 genetic intervention as well as publication of all data relevant to the presented conclusions. 

Scope

Cancer & Metabolism welcomes studies on all aspects of the relationship between cancer and metabolism, including:

• Molecular biology and genetics of cancer metabolism
• Whole-body metabolism, including diabetes and obesity, in relation to cancer
• Metabolomics in relation to cancer;
• Metabolism-based imaging
• Preclinical and clinical studies of metabolism-related cancer therapies.

This non-comprehensive list is meant to provide examples of appropriate themes, and we welcome work that may fit the aims of the journal even if it does not fall into the above categories.

Although novelty is not a requirement for publication, studies that are confirmatory of previous work should contain additional analyses or rigor beyond what has been reported in the literature.

Please note, Cancer & Metabolism publishes solicited reviews from time to time but rarely accepts unsolicited reviews. Any author considering submitting a review should contact the Editors in advance.

Examples of papers that are not in scope:

• Work that does not directly involve metabolites or metabolic pathways
• Bibliometric analyses
• Correlative studies, for example those assessing relationship between metabolite levels and disease metrics. Some exceptions may be made for datasets of unusual size, value, or scope, especially if there is additional analysis providing insight into the relationship between metabolism and cancer.
• Work lacking sufficient rigor. As a general principle, all findings should be repeated in 2 or more cell lines and genetic manipulation should include more than one sgRNA/shRNA and/or include appropriate cDNA rescues