Fig. 4

Heatmap of Correlations Between Potential Microbiota-derived Metabolites and Flow Cytometry Cytokines/Chemokines. (A) OC vs. GI, (B) OC II-III vs. OC IV, the heatmap illustrates the correlations between microbiota-derived metabolites and cytokines measured by flow cytometry. A single asterisk (*) indicates a significant correlation (p < 0.05), while a double asterisk (**) represents a highly significant correlation (p < 0.01). Correlations were calculated using Pearson method for normally distributed data. Abbreviations: LPI, Lysophosphatidylinositol