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Fig. 6 | Cancer & Metabolism

Fig. 6

From: ETV4/ALYREF-mediated glycolytic metabolism through PKM2 enhances resistance to ferroptosis and promotes the development of intrahepatic cholangiocarcinoma

Fig. 6

The ETV4/ALYREF axis promotes tumor proliferation and glycolytic metabolism in mice. (A) Images of subcutaneous xenograft in mice. (B) The effect of ETV4/ALYREF axis on subcutaneous xenograft volume. (C) The effect of ETV4/ALYREF axis on subcutaneous xenografts weight. (D) The effect of ETV4/ALYREF axis on the concentration of LD in subcutaneous xenografts. (E) WB analysis of the expression of PKM2 and its downstream targets in subcutaneous xenografts. *P < 0.05; **P < 0.01; ***P < 0.001; n = 6

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Cancer & Metabolism

ISSN: 2049-3002