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Fig. 1 | Cancer & Metabolism

Fig. 1

From: Carboxylesterase 1-mediated endocannabinoid metabolism in skin: role in melanoma progression in BRafV600E/Pten−/− mice

Fig. 1

Schematic representation of the 2-AG-ARA-PGs axis. Abbreviations: 2-AG, 2-arachidonoylglycerol; ABHD6, alpha/beta-hydrolase domain-containing protein 6; ABHD12, alpha/beta-hydrolase domain-containing protein 12; ARA, arachidonic acid; CES1, carboxylesterase 1; CES2, carboxylesterase 2; COX1, Cyclooxygenase 1 COX2, Cyclooxygenase 2; DAGL α, Diacylglycerol lipase α; DAGL β, Diacylglycerol lipase β; MAGL, monoacylglycerol lipase; PGD2, prostaglandin D2; PGE2, prostaglandin E2; SAG, 1-stearoyl-2-arachidonoyl-sn-glycerol

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Cancer & Metabolism

ISSN: 2049-3002