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Fig. 5 | Cancer & Metabolism

Fig. 5

From: Exploratory profiling of metabolites in cerebrospinal fluid using a commercially available targeted LC-MS based metabolomics kit to discriminate leptomeningeal metastasis

Fig. 5

Characteristics of discriminative metabolites for leptomeningeal metastasis, parenchymal brain tumor, and inflammatory disease. A Venn diagram of discriminative candidate metabolites between ‘LM diagnostic’ (LM vs. PBT) and ‘tumorous’ (PBT vs. HC) and ‘inflammatory’ (ID vs. HC) samples. B-C Box plots depicting levels of (B) threonine and (C) AC(4:0-OH) among patient groups. D Logistic regression model with three metabolites that were exclusive to the LM diagnostic profile. Notes: PBT, parenchymal brain metastasis; HC, healthy control; ID, inflammatory disease; LM, leptomeningeal metastasis; Thr, threonine

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Cancer & Metabolism

ISSN: 2049-3002