Fig. 1
From: RNF2 promotes chondrosarcoma progression by regulating ubiquitination and degradation of CBX7

High expression of RNF2 in CHS tissues and cells. Note: (A) RT-qPCR, (B) Western blot, and (C) immunohistochemistry (arrows indicate RNF2-positive cells) to detect RNF2 expression in CHS clinical samples (N = 25); **, P < 0.01 compared with the normal group; (D) RT-qPCR and (F) Western blot to detect RNF2 expression in CHS cell line. The cellular experiments were repeated three times, and the data were expressed as mean ± standard deviation. The independent samples t-test was used for comparisons between two groups, and one-way ANOVA was used for comparisons among multiple groups, with Tukey’s multiple comparisons test for post hoc analysis. **, P < 0.01, ***, P < 0.001 compared with the C-28/I2 group