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Fig. 3 | Cancer & Metabolism

Fig. 3

From: Metabolism of primary high-grade serous ovarian carcinoma (HGSOC) cells under limited glutamine or glucose availability

Fig. 3

The lack of two distinct clusters among tumor cell isolates stratified according to their proliferation (indirectly assessed by ATP levels) in glucose-deficient and glutamine-deficient media, expression of ETC proteins, ECAR, and OCR. (A) An overview of patient-matched data of CellTiter-Glo readouts of tumor cells grown in glucose- or glutamine-deficient media (lower part of the subfigure) compared with the expression of ETC proteins (upper part of the subfigure). The tumor cell isolates are sorted according to the ATP levels detected after cultivation in glutamine-deficient media. (B) An overview of patient-matched data of the ETC protein expression (lower part of the subfigure) compared with ECAR (middle part of the subfigure) and OCR (upper part of the subfigure) parameters. The tumor cell isolates are sorted according to the ETC IV expression levels

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Cancer & Metabolism

ISSN: 2049-3002