Fig. 2

Hypoxic cores develop in B16OVA.HRE and MC38.HRE spheroids. Spheroids formed from B16OVA and MC38 cells transduced with an HRE-eGFP-ODD construct induce eGFP under hypoxia over time as detected by the IncuCyte Live-cell imaging system
Hypoxic cores develop in B16OVA.HRE and MC38.HRE spheroids. Spheroids formed from B16OVA and MC38 cells transduced with an HRE-eGFP-ODD construct induce eGFP under hypoxia over time as detected by the IncuCyte Live-cell imaging system