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Fig. 7 | Cancer & Metabolism

Fig. 7

From: Elevated expression of HIGD1A drives hepatocellular carcinoma progression by regulating polyamine metabolism through c-Myc–ODC1 nexus

Fig. 7

HIGD1A knockdown targets c-Myc–ODC1 nexus to inhibit HCC tumor growth in xenografted nude mice model. A Images of HepG2, Huh7, and MHCC97H xenograft tumors in nude mice of the shCtrl group and shHIGD1A group (n = 5 mice per group). The middle and right graphs show the final weights of the tumors and the tumor growth curve, respectively. B Immunohistochemical staining of Ki67, c-Myc, and ODC1 in HepG2, Huh7, and MHCC97H subcutaneous xenograft tumor tissues from the shCtrl group and shHIGD1A group. Results shown are mean ± SEM. *P <0.05, **P <0.01, ***P <0.001. Scale bar, 50µm

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Cancer & Metabolism

ISSN: 2049-3002