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Fig. 4 | Cancer & Metabolism

Fig. 4

From: STEAP4 inhibits cisplatin-induced chemotherapy resistance through suppressing PI3K/AKT in hepatocellular carcinoma

Fig. 4

STEPA4 inhibits DDP-induced chemotherapy resistance in vivo. a Soft agar growth assay for the effect of STEAP4 overexpression or knockdown in DDP-induced cell growth. b Representative tumor images of orthotopic transplantation mouse model using STEAP4 overexpression or knockdown HCC cells treated with DDP. TUNEL assay was used to analyze the apoptosis of xenograft tumor tissues. c Kaplan-Meier curves with log rank test for orthotopic transplantation mouse model. d The concentration of AST and ALT of orthotopic transplantation mouse model. Bars represent the mean ± SD of three independent experiments; *P < 0.05

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Cancer & Metabolism

ISSN: 2049-3002