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Fig. 2 | Cancer & Metabolism

Fig. 2

From: STEAP4 inhibits cisplatin-induced chemotherapy resistance through suppressing PI3K/AKT in hepatocellular carcinoma

Fig. 2

STEAP4 overexpression inhibits DDP-induced chemotherapy resistance in vitro. a GSEA indicating significant correlation between STEAP4 expression and DDP-induced chemotherapy resistance generation. b Western blot analysis of STEAP4 expression in the indicated STEAP4-infected cells. GAPDH was used as the loading control. c Cell viability analysis for the effect of STEAP4 overexpression in DDP-induced cell proliferation. d Colony formation analysis for the effect of STEAP4 overexpression in DDP-induced cell proliferation. e Annexin/PI apoptosis analysis for the effect of STEAP4 overexpression in DDP-induced cell apoptosis. Bars represent the mean ± SD of three independent experiments; *P < 0.05

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Cancer & Metabolism

ISSN: 2049-3002