Fig. 2

Hierarchical clustering of plasma metabolites of healthy controls and patients with A stage IA EMC and B stage IB–IV EMC. Rows represent the concentration of each metabolite with a distinct metabolic pattern in patients with EMC and healthy controls. Blue and red bars indicate decreased and increased levels in patients with EMC, respectively, relative to healthy controls. The dendrogram on the left was codirected based on the metabolite concentration profiles