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Fig. 5 | Cancer & Metabolism

Fig. 5

From: TNF-α differentially modulates subunit levels of respiratory electron transport complexes of ER/PR +ve/−ve breast cancer cells to regulate mitochondrial complex activity and tumorigenic potential

Fig. 5

TNF-α sensitizes cell death and decreases growth in MDA-MB-231 cells. a MCF-7 and MDA-MB-231 cells were seeded in 12 well plates and scratch assay was performed in the presence of TNF-α. b, c MCF-7 and MDA-MB-231 cells were seeded at low denisty as described in methodology and their ability to form colonies in the presence and absence of TNF-α,2-DG, NAC, and pyruvate was monitored. d MDA-MB-231 cells were treated with TNF-α either alone or in combination with Hemin (10 mM) and the cell viability was assessed as described in methodology by MTT

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Cancer & Metabolism

ISSN: 2049-3002