Skip to main content
Figure 3 | Cancer & Metabolism

Figure 3

From: Mitochondrial reactive oxygen species and cancer

Figure 3

Reactive oxygen species modify cellular signaling. Hydrogen peroxide derived from either NOXs or the mitochondria can activate the PI3K pathway, the hypoxia-inducible factor (HIF) pathway, and metabolic adaptations. These modifications are essential to allowing the survival, growth, and proliferation fundamental to tumorigenesis.

Back to article page

Cancer & Metabolism

ISSN: 2049-3002